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I’ve never had issues like that myself

Steel series Rival 500. Highly recommended. I got it specifically because I wanted as many buttons as possible but in an actually ergonomic to press layout vs trying to feel out the numbers in a numpad layout. https://steelseries.com/gaming-mice/rival-500

You can rest your thumb on a spot in the middle that looks like a button but isn’t and you can also lock out the 2 bottom buttons below your thumb with a physical switch if they get in the way

Gaming

• EthosLab - most authentic Minecraft YouTuber around. No trash clickbait, cringeworthy attempts to appeal to children, ad spam, etc. Just a dude chilling out and playing Minecraft.

• Battle(non)sense - Tests various input lag reduction tech + strategies. Input Lag: Low DPI vs High DPI - turns out increasing your DPI can significantly reduce input lag! AMD AntiLag+ vs Nvidia Reflex - turns out not only does AMD’s solution trigger anti-cheat, but it also offen increases system latency.

• Marblr - High quality analysis of weird game behavior. Mostly Overwatch for now. Overwatch: The Effectiveness of Shield Spinning

• People Make Games - Videos about games and the gaming industry. Highly accessible to folks not familiar with the industry. Making Sense of VR Chat, the Metaverse People Actually Like

• NoClip - Crowd funded feature length video game documentaries. Making of Horizon Zero Dawn

Makers

• ColinFurze - builds crazy stuff and does an amazing job of it! Currently building an underground garage at his house that connects to his underground tunnel system.

• I Did a Thing - Australian man with a great sense of humor. Makes ridiculous stuff. Giant Beyblade destroys stuff

…more in Honytawk’s comment below

Science + Technology

• Applied Science - In depth videos about random science-y things this dude finds interesting. No clickbait, just an excited dude talking about a project he tried.

• Atomic Frontier - A lot like Tom Scott. He’s also a rare case where the video is more interesting than the title/thumbnail. Generally focused on science-y topics + has shockingly high production value considering the dude seems to be an overworked college student.

• NileRed/NileBlue - Crazy in depth chemistry videos. Personally find NileBlue more entertaining as he tends to explore things he’s not that great at.

• Practical Engineering - Explanations of various civil engineering concepts.

Other

• Krazam - Legendary comedy channel focused on software engineering related topics. Most famous video - microservices.

• You Suck At Cooking - Short videos presenting recipes in an entertaining way.

• Studio Binder ; High quality videos about all things movie/video production. Owned by a movie production software company so you’re gonna see ads for it in every video but SponsorBlock gets rid of that with no issues. Ultimate Guide to Camera Movement - Every Technique Explained