Second generation antipsychotic medications are not only dopamine antagonists but also potent serotonin antagonists. Regulating serotonin uptake can help stabilize mood, both with depression and elevated states. So possibly more to do with their effects on serotonin receptors than dopamine receptors. (Not a doctor but nothing I said can’t be confirmed with a quick google scholar search)

For me it helps with brain fog and memory and also the other psychiatric disorder I have, trichotillomania, which is very hard to treat. They also have anti manic activity in the second generation antipsychotics.

I don’t know the science and medicine, but Seroquel helps me sleep at night (I am bi-polar). When I was in my 20s, a much larger dose did nothing for me. Many years later, we tried it again because physiology changes. Now it works. Too much and it’s hard to wake up in the morning.

I still liked taking a strong dose of Halcyon better. I could pop up in the morning feeling fantastic. But my current doc won’t let me have it except when I need to wake up and drive in the morning because it’s “habit-forming.” The Seroquel leaves me a little hazy for a while, so when we were two days in office after the pan rescinded, that’d be a Halcyon sleep. Luckily, my current gig is a ten minute walk from home.