TL;DW:
Does It Make Sense To Put Data Centers In Space?
At some point in the future, yes.
Can They Really Cost Less To Operate?
In theory, yes.
Scott expresses concerns that current startups have not adequately addressed some of the practical challenges, such as cooling.
Yea, this is a solved problem. Look at Hubble with the Gyroscopes problems, hell even voyager problem early this year.
…neither of which are applicable to data centers. they are very different beasts.